The CD300a Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CD300a. This antibody recognizes Human antigen. The CD300a Polyclonal Antibody has been validated for the following applications: Immunohistochemistry, and Immunohistochemistry - fixed.
Description
Inhibitory receptor which may contribute to the down- regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation (PubMed:16339535, PubMed:9701027). Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6 (PubMed:22043923)